Development and Validation of a Nomogram Prognostic Model for Patients With Advanced Non-Small-Cell Lung Cancer.

ABSTRACT:

Importance

Nomogram prognostic models can facilitate cancer patient treatment plans and patient enrollment in clinical trials.

Objective

The primary objective is to provide an updated and accurate prognostic model for predicting the survival of advanced non-small-cell lung cancer (NSCLC) patients, and the secondary objective is to validate a published nomogram prognostic model for NSCLC using an independent patient cohort.

Design

1817 patients with advanced NSCLC from the control arms of 4 Phase III randomized clinical trials were included in this study. Data from 524 NSCLC patients from one of these trials were used to validate a previously published nomogram and then used to develop an updated nomogram. Patients from the other 3 trials were used as independent valid

SUBMITTER: Wang T 

PROVIDER: S-EPMC6452590 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature