Automatic labeling of cortical sulci for the human fetal brain based on spatio-temporal information of gyrification.

ABSTRACT: Accurate parcellation and labeling of primary cortical sulci in the human fetal brain is useful for regional analysis of brain development. However, human fetal brains show large spatio-temporal changes in brain size, cortical folding patterns, and relative position/size of cortical regions, making accurate automatic sulcal labeling challenging. Here, we introduce a novel sulcal labeling method for the fetal brain using spatio-temporal gyrification information from multiple fetal templates. First, spatial probability maps of primary sulci are generated on the templates from 23 to 33 gestational weeks and registered to an individual brain. Second, temporal weights, which determine the level of contribution to the labeling for each template, are defined by similarity of gyrification between

SUBMITTER: Yun HJ 

PROVIDER: S-EPMC6452886 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature