Early health technology assessment of future clinical decision rule aided triage of patients presenting with acute chest pain in primary care.

ABSTRACT: The objective of the paper is to estimate the number of patients presenting with chest pain suspected of acute coronary syndrome (ACS) in primary care and to calculate possible cost effects of a future clinical decision rule (CDR) incorporating a point-of-care test (PoCT) as compared with current practice. The annual incidence of chest pain, referrals and ACS in primary care was estimated based on a literature review and on a Dutch and Belgian registration study. A health economic model was developed to calculate the potential impact of a future CDR on costs and effects (ie, correct referral decisions), in several scenarios with varying correct referral decisions. One-way, two-way, and probabilistic sensitivity analyses were performed to test robustness of the model outcome to changes in i

SUBMITTER: Willemsen RTA 

PROVIDER: S-EPMC6452953 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature