Patient and aneurysm characteristics in familial intracranial aneurysms. A systematic review and meta-analysis.

ABSTRACT:

Background and purpose

Patient and aneurysm characteristics have been reported to differ between patients with familial and non-familial intracranial aneurysms (IAs), although results are inconsistent. We systematically reviewed and meta-analyzed the literature to identify and quantify patient- and aneurysm characteristics associated with familial IAs.

Methods

We searched PubMed and EMBASE for case-control and cohort studies comparing patient- and aneurysm characteristics between familial and non-familial IAs. Two observers independently assessed study eligibility and appraised quality with the Newcastle Ottawa Scale. With univariable weighted linear regression analysis we calculated β-coefficients with corresponding 95% confidence intervals (CIs) for ruptured and unruptured

SUBMITTER: Slot EMH 

PROVIDER: S-EPMC6453525 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature