Association of Family History With Cancer Recurrence, Survival, and the Incidence of Colorectal Adenoma in Patients With Colorectal Cancer.

ABSTRACT:

Background

The influence of family history (FH) on cancer recurrence and survival among patients with established colorectal cancer (CRC) remains uncertain. This study aimed to evaluate the association of FH with cancer recurrence, survival, and the incidence of colorectal adenomas in patients with CRC.

Methods

Consecutive patients with stage III CRC diagnosed between 2004 and 2009 and followed-up in Severance Hospital were retrospectively enrolled and followed until December 2014. Overall survival (OS) and disease-free survival (DFS) according to FH of CRC or colorectal neoplasm were evaluated using Cox proportional hazards regression and Kaplan-Meier curve.

Results

Among analyzed 979 patients, 69 (7.0%) was identified as having a FH of CRC in a first-degree relative

SUBMITTER: Park Y 

PROVIDER: S-EPMC6453592 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature