The Impact of Dementia Diagnosis on Patterns of Potentially Inappropriate Medication Use Among Older Adults.

ABSTRACT:

Background

Use of potentially inappropriate medications (PIM) among people with dementia is common. We assessed the patterns of medication use from 1-year before dementia diagnosis, to 1-year after dementia diagnosis, compared with patterns of medication use in people without dementia.

Methods

We conducted longitudinal study using the National Alzheimer's Coordinating Center data. Adults aged 65 years and older newly diagnosed with dementia (n = 2,418) during 2005-2015 were year, age, and sex matched 1:1 with controls. Generalized estimating equation models weighted for missingness and adjusted for 15 participant characteristics were fit.

Results

Among participants with dementia, number of medications reported 1-year prediagnosis was 8% lower than at diagnosis year (p

SUBMITTER: Gnjidic D 

PROVIDER: S-EPMC6454446 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature