Anemia of Inflammation during Human Pregnancy Does Not Affect Newborn Iron Endowment.

ABSTRACT:

Background

To our knowledge, no studies have addressed whether maternal anemia of inflammation (AI) affects newborn iron status, and few have addressed risk factors for specific etiologies of maternal anemia.

Objectives

The study aims were to evaluate 1) the contribution of AI and iron deficiency anemia (IDA) to newborn iron endowment, 2) hepcidin as a biomarker to distinguish AI from IDA among pregnant women, and 3) risk factors for specific etiologies of maternal anemia.

Methods

We measured hematologic biomarkers in maternal blood at 12 and 32 wk of gestation and in cord blood from a randomized trial of praziquantel in 358 pregnant women with Schistosoma japonicum in The Philippines. IDA was defined as anemia with serum ferritin <30 ng/mL and non-IDA (NIDA), largely

SUBMITTER: Abioye AI 

PROVIDER: S-EPMC6454452 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature