Association of serum magnesium with all-cause mortality in patients with and without chronic kidney disease in the Dallas Heart Study.

ABSTRACT:

Background

Low serum magnesium (SMg) has been linked to increased mortality and cardiovascular disease (CVD) in the general population. We examined whether this association is similar in participants with versus without prevalent chronic kidney disease (CKD) in the multiethnic Dallas Heart Study (DHS) cohort.

Methods

SMg was analyzed as a continuous variable and divided into tertiles. Study outcomes were all-cause death, cardiovascular (CV) death or event, and CVD surrogate markers, evaluated using multivariable Cox regression models adjusted for demographics, comorbidity, anthropometric and biochemical parameters including albumin, phosphorus and parathyroid hormone, and diuretic use. Median follow-up was 12.3 years (11.9-12.8, 25th percentile-75th percentile).

Results</

SUBMITTER: Ferre S 

PROVIDER: S-EPMC6454476 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature