Contact Location and Neuropsychological Outcomes in Subthalamic Deep Brain Stimulation.

ABSTRACT:

Background

A host of influences contribute to cognitive and behavioral changes following deep brain stimulation. The location of the active cathode is likely an important variable but it has received little attention.

Objective

To determine whether active contact location relative to the subthalamic nucleus and other neighboring structures is related to nonmotor outcomes.

Methods

We identified a retrospective, cross-sectional sample of 46 patients who underwent subthalamic nucleus deep brain stimulation for treatment of idiopathic Parkinson's disease. T-tests or nonparametric equivalents were used to detect baseline differences between unilateral left, unilateral right, and bilateral surgical groups. Correlation and partial correlational analyses identified relationsh

SUBMITTER: Floden DP 

PROVIDER: S-EPMC6454795 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature