Validation of Alternative Methods for Detecting Meibomian Gland Dropout Without an Infrared Light System: Red Filter for Simple and Effective Meibography.

ABSTRACT:

Purpose

To evaluate the validity and reliability of alternative methods for evaluating meibomian gland (MG) dropout without using an infrared light system: red-filtered or isolated red-channel images (RCIs) of the everted eyelid.

Methods

We evaluated MG dropout in the everted upper and lower eyelids of 125 eyes of 64 patients with good-quality infrared meibography images (IMIs) and color digital photographs with and without a red filter. Red-filtered images (RFIs) were converted to black and white and adjusted for contrast/brightness [adjusted red-filtered images (aRFIs)]. RCIs were computationally isolated from color digital photographs obtained without a red filter. After randomization, the total meiboscore (0-6) was evaluated by 2 independent evaluators (interobserver rel

SUBMITTER: Lee SM 

PROVIDER: S-EPMC6455092 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature