Recruiting general practice patients for large clinical trials: lessons from the Aspirin in Reducing Events in the Elderly (ASPREE) study.

ABSTRACT:

Objective

To assess the factors that contributed to the successful completion of recruitment for the largest clinical trial ever conducted in Australia, the Aspirin in Reducing Events in the Elderly (ASPREE) study.

Design

Enrolment of GPs; identification of potential participants in general practice databases; screening of participants.

Setting, participants

Selected general practices across southeast Australia (Tasmania, Victoria, Australian Capital Territory, New South Wales, South Australia).

Major outcomes

Numbers of patients per GP screened and randomised to participation; geographic and demographic factors that influenced screening and randomising of patients.

Results

2717 of 5833 GPs approached (47%) enrolled to recruit patients for the study; 205

SUBMITTER: Lockery JE 

PROVIDER: S-EPMC6456041 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature