Long-term exposure to high altitude attenuates verbal and spatial working memory: Evidence from an event-related potential study.

ABSTRACT:

Introduction

This study aimed to determine the neurocognitive basis underlying the effects of long-term high-altitude (HA) exposure on working memory (WM).

Methods

Using event-related potentials (ERPs), we compared the performance of an HA group (individuals who had lived at HA for 3 years but were born and raised at low altitude [LA]) to that of an LA group (individuals who had only lived at LA) on verbal and spatial n-back tasks (i.e., 1- and 2-back memory load).

Results

Response accuracy of the HA group was significantly decreased in comparison to the LA group in both the verbal and spatial 2-back tasks. The P2 amplitude was larger in the HA than in the LA group in the spatial, but not the verbal 2-back task. A smaller late-positive potential (LPP) amplitude was fo

SUBMITTER: Ma H 

PROVIDER: S-EPMC6456776 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature