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Low pathogenic avian influenza (H7N6) virus causing an outbreak in commercial Turkey farms in Chile.


ABSTRACT: In late 2016, an H7N6 low pathogenic avian influenza virus outbreak occurred in domestic turkeys in Central Chile. We characterized the genetic and antigenic properties of the outbreak virus and its experimental transmission in chickens. Our studies demonstrate that the outbreak virus is a reassortment of genes identified from Chilean wild bird viruses between 2013 and 2017 and displays molecular adaptations to poultry and antiviral resistance to adamantanes. Further, these wild bird viruses are also able to transmit in experimentally infected chickens highlighting the need for continued surveillance and improvement of biosecurity in poultry farms.

SUBMITTER: Jimenez-Bluhm P 

PROVIDER: S-EPMC6456847 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Low pathogenic avian influenza (H7N6) virus causing an outbreak in commercial Turkey farms in Chile.

Jimenez-Bluhm Pedro P   Bravo-Vasquez Nicolas N   Torchetti Mia K MK   Killian Mary L ML   Livingston Brandi B   Herrera Jose J   Fuentes Mauricio M   Schultz-Cherry Stacey S   Hamilton-West Christopher C  

Emerging microbes & infections 20190101 1


In late 2016, an H7N6 low pathogenic avian influenza virus outbreak occurred in domestic turkeys in Central Chile. We characterized the genetic and antigenic properties of the outbreak virus and its experimental transmission in chickens. Our studies demonstrate that the outbreak virus is a reassortment of genes identified from Chilean wild bird viruses between 2013 and 2017 and displays molecular adaptations to poultry and antiviral resistance to adamantanes. Further, these wild bird viruses are  ...[more]

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