Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank cohort.

ABSTRACT:

Background

Multimorbidity is associated with higher mortality, but the relationship with cancer and cardiovascular mortality is unclear. The influence of demographics and type of condition on the relationship of multimorbidity with mortality remains unknown. We examine the relationship between multimorbidity (number/type) and cause of mortality and the impact of demographic factors on this relationship.

Methods

Data source: the UK Biobank; 500,769 participants; 37-73 years; 53.7% female. Exposure variables: number and type of long-term conditions (LTCs) (N = 43) at baseline, modelled separately. Cox regression models were used to study the impact of LTCs on all-cause/vascular/cancer mortality during median 7-year follow-up. All-cause mortality regression models were stratifi

SUBMITTER: Jani BD 

PROVIDER: S-EPMC6456941 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature