Characterization of minimal lesions related to the presence of visna/maedi virus in the mammary gland and milk of dairy sheep.

ABSTRACT:

Background

In order to characterize the complete range of lesions, especially minimal, affecting mammary gland and viral antigen distribution and target cells using immunohistochemistry in naturally Visna/maedi (VM) 84 infected sheep were studied, forty-four from flocks with clinical cases (A) and 35 randomly sampled from two abattoirs (B) together with five negative controls (C). An immunocytochemistry technique was developed and further milk samples (n = 39) were used to study viral excretion, carrier cells and the role of milk and colostrum in the transmission of the disease.

Results

All sheep from group C and three sheep from group B were negative to VM in tissue sections by histopathology, immunohistochemistry and PCR, and also in serum using ELISA. Several degrees of C

SUBMITTER: Gayo E 

PROVIDER: S-EPMC6456970 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature