Prospective Study of Glycated Hemoglobin and Trajectories of Depressive Symptoms: The China Health and Retirement Longitudinal Study.

ABSTRACT: The longitudinal association between glycated hemoglobin (HbA_1c) and different courses of depressive symptoms is understudied. This study aimed to identify different trajectories of depressive symptoms and investigate the relation of HbA_1c with the risk of increasing and high-stable depressive symptoms. In the China Health and Retirement Longitudinal Study, depressive symptoms were measured using the 10-item Center for Epidemiological Studies-Depression scale in three visits (years: 2011, 2013 and 2015) among 9804 participants (mean age 60.0 ± 9.0 years). Group-based trajectory modeling was used to identify trajectories of depressive symptoms. HbA_1c was measured at baseline and categorized five groups according to the respective quintile. Multinomial logist

SUBMITTER: Li H 

PROVIDER: S-EPMC6457062 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature