Gut microbiota and overweight in 3-year old children.

ABSTRACT:

Background

The gut microbiota has been associated with overweight and obesity in adults, but the evidence in children is limited. Our aim was to study whether composition of the gut microbiota at the age of 3 years is associated with overweight/obesity in children cross-sectionally.

Methods

Children, who participated in a clinical trial of prenatal vitamin-D supplementation (VDAART), underwent standardized height and weight measurements, and collection of stool samples at 3 years of age. 16 S rRNA sequencing (V4 region) of the stool samples were performed with Illumina MiSeq. Associations between microbiota and overweight/obesity (body mass index z-scores >85th percentile) was analyzed using logistic regression.

Results

Out of 502 children, 146 (29%) were categorized

SUBMITTER: Karvonen AM 

PROVIDER: S-EPMC6457121 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature