Associations between lipids and subclinical coronary atherosclerosis.

ABSTRACT:

Objective

Whether HIV modifies the relationship of serum lipids with coronary atherosclerosis and coronary plaque subtypes is uncertain. We examined the associations between traditional lipids and coronary atherosclerosis among HIV-infected (HIV+) and HIV-uninfected (HIV-) men.

Design

The Multicenter AIDS Cohort Study is an observational cohort with a total of 429 HIV+ and 303 HIV- men who had non-contrast cardiac computed tomography performed to measure coronary artery calcium and coronary computed tomography angiography to measure coronary stenosis, coronary plaque presence, and composition.

Methods

We used multivariable adjusted prevalence ratios to examine the relationship between the SD difference in each lipid parameter and coronary atherosclerosis.

Results</

SUBMITTER: Whelton SP 

PROVIDER: S-EPMC6457132 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature