Acute bladder decentralization in hound dogs: Preliminary results of effects on hypogastric nerve electroneurograms and detrusor pressure responses to spinal root and hypogastric nerve stimulation.

ABSTRACT:

Objective

We aimed to refine electroneurogram techniques for monitoring hypogastric nerve activity during bladder filling, and then examined nerve activity in normal intact versus acutely decentralized bladders.

Methods

Effects of electrical stimulation of hypogastric nerves or lumbar ventral roots on detrusor pressure were examined, as were effects of isoflurane versus propofol anesthetics on hypogastric nerve stimulation evoked pressure. Hypogastric nerve activity was then recorded using custom-made bipolar cuff electrodes during bladder filling before and after its transection between the spinal cord and electrode to eliminate efferent nerve signals.

Results

Electrical stimulation of hypogastric nerves evoked low amplitude detrusor pressures that did not differ bet

SUBMITTER: Tiwari E 

PROVIDER: S-EPMC6457673 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature