Decreasing the Toxicity of Radiation Therapy: Radioprotectors and Radiomitigators Being Developed by the National Cancer Institute Through Small Business Innovation Research Contracts.

ABSTRACT:

Purpose

The use of radioprotectors and radiomitigators could improve the therapeutic index of radiation therapy. With the intention of accelerating translation of radiation-effect modulators (radioprotectors and mitigators), the Radiation Research Program and SBIR (Small Business Innovation Research) Development Center within the National Cancer Institute issued 4 Requests for Proposals (RFPs) from 2010 to 2013. Twelve SBIR contract awards in total were made in response to the 4 RFPs from September 2011 through September 2014. Here, we provide an update on the status of SBIR contract projects for the development of radiation-effect modulators.

Methods and materials

To assess the status of research and development efforts under the 4 RFPs on radiation-effect modulators, we se

SUBMITTER: Zakeri K 

PROVIDER: S-EPMC6458068 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature