Molecular Mechanism of Antibiotic Resistance: The Untouched Area of Future Hope.

ABSTRACT: The treatment of bacterial infections is becoming increasingly ineffective due to rapid mutation which leads to antibiotic resistant and resistant bacteria become more prevalent. As a result the existing antibiotics are gradually obsolete and again new drugs are needed to be designed for the same threat. However, the prediction of evolutionary processes/antibiotic resistance is uncertain. Still, the understanding of mode of evolution of resistance in bacteria is a determining step in the preclinical development of new antibiotics, because drug developers assess the risk of resistance arising against a drug during preclinical development. Multidrug efflux pump systems play an important role for making multidrug resistance to a range of clinically important antibiotics in gram-negative bacte

SUBMITTER: Biswas R 

PROVIDER: S-EPMC6458223 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature