Insulin and incretin hormone responses to rapid versus slow ingestion of a standardized solid breakfast in healthy subjects.

ABSTRACT: People with repeated rapid meal ingestion have been reported to have increased risk of insulin resistance, impaired glucose tolerance and obesity. To explore whether speed of eating a breakfast influences the postprandial rise of glucose, insulin and the incretin hormones, 24 healthy subjects (12 men and 12 women, mean age 62 years) ingested a standardized solid breakfast consisting of 524 kcal (60% from carbohydrate, 20% from protein, 20% from fat) over 5 or 12 minutes on separate days in random order. Breakfast ingestion increased circulating glucose and insulin with maximal levels seen at 30 minutes after start of meal ingestion with no significant difference in the two tests. Similarly, breakfast increased circulating levels of total (reflecting secretion) glucose-dependent insulinotro

SUBMITTER: Alsalim W 

PROVIDER: S-EPMC6458458 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature