Availability of suPAR in emergency departments may improve risk stratification: a secondary analysis of the TRIAGE III trial.

ABSTRACT:

Introduction

Soluble urokinase plasminogen activator receptor (suPAR) is a prognostic and nonspecific biomarker associated with short-term mortality in emergency department (ED) patients. Therefore, the blood level of suPAR might be usable for identification of patients at high- and low risk, shortly after arrival at the ED. Here, we investigate the value of adding suPAR to triage and how this may impact on risk stratification regarding mortality.

Methods

The analyses were performed on the TRIAGE III cohort. Patients were triaged in four groups: Red, Orange, Yellow, and Green. Outcome was all-cause mortality within seven days. Discriminative abilities of triage and suPAR on mortality were assessed using the area under the curve (AUC) for receiver operating characteristics (R

SUBMITTER: Schultz M 

PROVIDER: S-EPMC6458624 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature