Analysis of long non-coding RNAs in neonatal piglets at different stages of porcine deltacoronavirus infection.

ABSTRACT:

Background

PDCoV (Porcine Deltacoronavirus) is a novel porcine coronavirus that causes intestinal necrosis of piglets, thinning of the intestinal wall and severe villus atrophy in the small intestine. PDCoV is a highly contagious infectious disease characterized by diarrhea, dehydration and vomiting. It has been reported that lncRNA has a significant effect on viral replication and increased or decreased virulence. At present, there is almost no research on lncRNA related to PDCoV infection. With the development of the research, a large number of lncRNAs related to PDCoV infection have been discovered. Identifying the role of these lncRNAs in the infection process facilitates the screening of diagnostically significant biomarkers.

Results

Using high throughput sequencing to

SUBMITTER: Tang X 

PROVIDER: S-EPMC6458635 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature