Evidence that the stress hormone cortisol regulates biofilm formation differently among Flavobacterium columnare isolates.

ABSTRACT: The impact of cortisol on Flavobacterium columnare biofilm formation was explored. Firstly, the dynamics of biofilm formation by one highly (HV) and one low virulent (LV) F. columnare isolate with and without the stress hormone cortisol under microfluidic flow conditions was characterized. This to confirm that F. columnare cells could form biofilm under cortisol supplementation, and to compare the temporal and structural differences between different treatment groups. One trial revealed that in both isolates cell aggregates resembling biofilms occurred within 7-h post-inoculation. Consequently, cell clusters were sloughed away, followed by a rebuilding of bacterial cell aggregates, suggestive for a high spreading capacity. While the HV isolate revealed cell aggregates formed upstream at al

SUBMITTER: Declercq AM 

PROVIDER: S-EPMC6458827 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature