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Psychometric Properties of the Apathy Scale in Advanced Parkinson's Disease.


ABSTRACT:

Objectives

To assess the psychometric attributes of the Apathy Scale- (AS-) Spanish version in patients with advanced Parkinson's disease (APD).

Materials and methods

Over 6 months, 61 patients participated in a clinical study of levodopa-carbidopa intestinal gel (LCIG) and were evaluated using the AS and other clinical tools. Various psychometric attributes of the AS were assessed.

Results

Patients (60.7% men) were aged 68.02 ± 7.43 years, with 12.57 ± 5.97 years from PD diagnosis. Median HY of patients in "on state" was 2 (range, 1-4), and mean levodopa equivalent daily dose was 1455.98 ± 456.00 mg. Overall, the parameters of feasibility/acceptability were satisfactory, except for a moderate-to-high floor effect in AS items but not in its total score (both 3.3%). Cr

SUBMITTER: Wetmore JB 

PROVIDER: S-EPMC6458845 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature