Association of Systemic Antibiotic Treatment of Acne With Skin Microbiota Characteristics.

ABSTRACT:

Importance

Given the widespread use of systemic antibiotics for treatment of moderate to severe acne, it is important to understand the associations of such antibiotic use with changes not only in Cutibacterium acnes (formerly Propionibacterium acnes) but also in the complete bacterial community of the skin.

Objective

To examine the composition, diversity, and resilience of skin microbiota associated with systemic antibiotic perturbation in individuals with acne.

Design, setting, and participants

This longitudinal cohort study conducted at an academic referral center in Maryland from February 11 to September 23, 2014, included 4 female participants who had received a recent diagnosis of acne vulgaris, showed comedonal and inflammatory acne on the face, were at least 1

SUBMITTER: Chien AL 

PROVIDER: S-EPMC6459106 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature