Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy.

ABSTRACT:

Importance

The watch-and-wait (WW) strategy aims to spare patients with rectal cancer unnecessary resection.

Objective

To analyze the outcomes of WW among patients with rectal cancer who had a clinical complete response to neoadjuvant therapy.

Design, setting, and participants

This retrospective case series analysis conducted at a comprehensive cancer center in New York included patients who received a diagnosis of rectal adenocarcinoma between January 1, 2006, and January 31, 2015. The median follow-up was 43 months. Data analyses were conducted from June 1, 2016, to October 1, 2018.

Exposures

Patients had a clinical complete response after completing neoadjuvant therapy and agreed to a WW strategy of active surveillance and possible salvage surgery (n = 113),

SUBMITTER: Smith JJ 

PROVIDER: S-EPMC6459120 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature