Frequency of Porphyromonas gingivalis fimA in smokers and nonsmokers after periodontal therapy.

ABSTRACT: Porphyromonas gingivalis is one of the most important Gram-negative anaerobe bacteria involved in the pathogenesis of periodontitis. P. gingivalis has an arsenal of specialized virulence factors that contribute to its pathogenicity. Among them, fimbriae play a role in the initial attachment and organization of biofilms. Different genotypes of fimA have been related to length of fimbriae and pathogenicity of the bacterium.

Objectives

The aim of this study was to identify 5 types of fimA genotype strains in smokers and nonsmokers with periodontitis, before and after periodontal therapy.

Material and methods

Thirty-one patients with periodontitis harboring P. gingivalis were selected: 16 nonsmokers (NS) and 15 smokers (SM). Clinical and microbiological parameters were evaluated

SUBMITTER: Abreu MGL 

PROVIDER: S-EPMC6459229 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature