The Macaque Cerebellar Flocculus Outputs a Forward Model of Eye Movement.

ABSTRACT: The central nervous system (CNS) achieves fine motor control by generating predictions of the consequences of the motor command, often called forward models of the movement. These predictions are used centrally to detect not-self generated sensations, to modify ongoing movements, and to induce motor learning. However, finding a neuronal correlate of forward models has proven difficult. In the oculomotor system, we can identify neuronal correlates of forward models vs. neuronal correlates of motor commands by examining neuronal responses during smooth pursuit at eccentric eye positions. During pursuit, torsional eye movement information is not present in the motor command, but it is generated by the mechanic of the orbit. Importantly, the directionality and approximate magnitude of torsiona

SUBMITTER: Kim G 

PROVIDER: S-EPMC6460257 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature