The impact of early-life intelligence quotient on post stroke cognitive impairment.

ABSTRACT:

Background

Cognitive impairment can complicate minor stroke, but there is limited information on risk factors including peak cognitive ability earlier in life.

Methods

We recruited patients with clinically-evident lacunar or minor non-lacunar ischaemic stroke, recorded clinical features, vascular risk factors, magnetic resonance imaging-detected stroke sub-type and small vessel disease burden. At 1-3 and 12 months after stroke, we assessed educational attainment (years of education), current cognition (Addenbrooke's Cognitive Examination-Revised), pre-morbid intelligence (National Adult Reading Test) and dependency (modified Rankin Scale).

Results

We recruited 157 patients (87 lacunar, 64 non-lacunar ischaemic strokes), median age 66 (inter-quartile range 56-74) years

SUBMITTER: Makin SD 

PROVIDER: S-EPMC6460404 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature