Treatment use in prognostic model research: a systematic review of cardiovascular prognostic studies.

ABSTRACT:

Background

Ignoring treatments in prognostic model development or validation can affect the accuracy and transportability of models. We aim to quantify the extent to which the effects of treatment have been addressed in existing prognostic model research and provide recommendations for the handling and reporting of treatment use in future studies.

Methods

We first describe how and when the use of treatments by individuals in a prognostic study can influence the development or validation of a prognostic model. We subsequently conducted a systematic review of the handling and reporting of treatment use in prognostic model studies in cardiovascular medicine. Data on treatment use (e.g. medications, surgeries, lifestyle interventions), the timing of their use, and the handling o

SUBMITTER: Pajouheshnia R 

PROVIDER: S-EPMC6460846 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature