Multilevel Mapping of Sexual Dimorphism in Intrinsic Functional Brain Networks.

ABSTRACT: Differences in cognitive performance between males and females are well-described, most commonly in certain spatial and language tasks. Sex-related differences in cognition are relevant to the study of the neurotypical brain and to neuropsychiatric disorders, which exhibit prominent disparities in the incidence, prevalence and severity of symptoms between men and women. While structural dimorphism in the human brain is well-described, controversy exists regarding the existence and degree of sex-related differences in brain function. We analyzed resting-state functional MRI from 650 neurotypical young adults matched for age and sex to determine the degree of sexual dimorphism present in intrinsic functional networks. Multilevel modeling was pursued to create 8-, 24-, and 51-network models o

SUBMITTER: de Lacy N 

PROVIDER: S-EPMC6460937 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature