The inflammatory potential of diet in determining cancer risk; A prospective investigation of two dietary pattern scores.

ABSTRACT:

Purpose

Inflammation-related mechanisms may contribute to the link between diet and cancer. We sought to investigate the inflammatory impact of diet on cancer risk using the Dietary inflammatory index (DII) and an adapted Mediterranean diet score (MDS).

Methods

This population-based, prospective cohort study used self-reported dietary data from the Västerbotten Intervention Programme, including 100,881 participants, of whom 35,393 had repeated measures. Associations between dietary patterns and cancer risk were evaluated using Cox proportional hazards regression. We also used restricted cubic splines to test for potential non-linear associations.

Results

A total of 9,250 incident cancer cases were diagnosed during a median follow-up of 15 years. The two dietary patter

SUBMITTER: Boden S 

PROVIDER: S-EPMC6461253 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature