Atypical functional connectivity in adolescents and adults with persistent and remitted ADHD during a cognitive control task.

ABSTRACT: We previously provided initial evidence for cognitive and event-related potential markers of persistence/remission of attention-deficit/hyperactivity disorder (ADHD) from childhood to adolescence and adulthood. Here, using a novel brain-network connectivity approach, we aimed to examine whether task-based functional connectivity reflects a marker of ADHD remission or an enduring deficit unrelated to ADHD outcome. High-density EEG was recorded in a follow-up of 110 adolescents and young adults with childhood ADHD (87 persisters, 23 remitters) and 169 typically developing individuals during an arrow-flanker task, eliciting cognitive control. Functional connectivity was quantified with network-based graph-theory metrics before incongruent (high-conflict) target onset (pre-stimulus), during ta

SUBMITTER: Michelini G 

PROVIDER: S-EPMC6461684 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature