Feed-forward information and zero-lag synchronization in the sensory thalamocortical circuit are modulated during stimulus perception.

ABSTRACT: The direction of functional information flow in the sensory thalamocortical circuit may play a role in stimulus perception, but, surprisingly, this process is poorly understood. We addressed this problem by evaluating a directional information measure between simultaneously recorded neurons from somatosensory thalamus (ventral posterolateral nucleus, VPL) and somatosensory cortex (S1) sharing the same cutaneous receptive field while monkeys judged the presence or absence of a tactile stimulus. During stimulus presence, feed-forward information (VPL → S1) increased as a function of the stimulus amplitude, while pure feed-back information (S1 → VPL) was unaffected. In parallel, zero-lag interaction emerged with increasing stimulus amplitude, reflecting externally driven thalamocortical synch

SUBMITTER: Tauste Campo A 

PROVIDER: S-EPMC6462113 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature