Population-based study of early-onset neonatal sepsis in Canada.

ABSTRACT:

Objective

To determine the incidence, types of organisms and resistance patterns involved in early-onset neonatal sepsis in Canada.

Study design

Early-onset neonatal sepsis cases were identified through the Canadian Paediatric Surveillance Program. Neonates were excluded if they were asymptomatic or if intracranial procedures preceded a positive cerebrospinal fluid culture.

Results

One hundred and twenty-seven cases were identified (0.17 cases per 1000 live births). Group B Streptococcus accounted for 41.7%, Escherichia coli for 35.4%. Antibiotic resistance was present in 33.9% of all cases. 55.6% of E coli cases were resistant, most commonly to ampicillin. Infecting organism species were associated with gestational age, being very low birth weight, time

SUBMITTER: Sgro M 

PROVIDER: S-EPMC6462127 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature