Macular Morphology and Visual Acuity in Year Five of the Comparison of Age-related Macular Degeneration Treatments Trials.

ABSTRACT:

Purpose

To evaluate associations of morphologic features with 5-year visual acuity (VA) in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT).

Design

Cohort study within a randomized clinical trial.

Participants

Participants in CATT.

Methods

Eyes with age-related macular degeneration-associated choroidal neovascularization (CNV) and VA between 20/25 and 20/320 were eligible. Treatment was assigned randomly to ranibizumab or bevacizumab and to 3 dosing regimens for 2 years and was at the ophthalmologists' discretion thereafter.

Main outcome measures

Visual acuity, thickness and morphologic features on OCT, and lesion size and foveal composition on fundus photography (FP) and fluorescein angiography (FA).

Results

Visual acui

SUBMITTER: Jaffe GJ 

PROVIDER: S-EPMC6462189 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature