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Nutritional status and clinical outcomes in pediatric patients with solid tumors : A systematic review of the literature.


ABSTRACT:

Introduction

Nutritional status (NS), defined by undernutrition (body mass index [BMI] <5th percentile) or overnutrition (BMI  ≥ 85th percentile), is a poor prognostic indicator in pediatric oncology patients. The impact of NS has been primarily studied in hematologic malignancies. This review is intended to summarize literature reporting on the association of NS and treatment-related outcomes in pediatric solid tumors.

Methods

We searched four electronic databases from inception through August 2018 without language restriction, and included studies of children with cancers arising from renal, bone, liver, eye, muscle, vascular, germ cell, and neural crest tissues, reporting on NS as a predictor for toxicity, survival or relapse. Due to data heterogeneity and limited availab

SUBMITTER: Joffe L 

PROVIDER: S-EPMC6462401 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature