Effects of Severe Hypoglycemia on Cardiovascular Outcomes and Death in the Veterans Affairs Diabetes Trial.

ABSTRACT:

Objective

To determine the risk factors for severe hypoglycemia and the association between severe hypoglycemia and serious cardiovascular adverse events and cardiovascular and all-cause mortality in the Veterans Affairs Diabetes Trial (VADT).

Research design and methods

This post hoc analysis of data from the VADT included 1,791 military veterans (age 60.5 ± 9.0 years) with suboptimally controlled type 2 diabetes (HbA_1c 9.4 ± 2.0%) of 11.5 ± 7.5 years disease duration with or without known cardiovascular disease and additional cardiovascular risk factors. Participants were randomized to intensive (HbA_1c <7.0%) versus standard (HbA_1c <8.5%) glucose control.

Results

The rate of severe hypoglycemia in the intensive treatment group was 10

SUBMITTER: Davis SN 

PROVIDER: S-EPMC6463547 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature