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Molecular Characterization of African Swine Fever Viruses from Outbreaks in Peri-Urban Kampala, Uganda.


ABSTRACT: African swine fever (ASF) is an infectious transboundary disease of domestic pigs and wild swine and is currently the most serious constraint to piggery in Uganda. The causative agent of ASF is a large double-stranded linear DNA virus with a complex structure. There are twenty-four ASFV genotypes described to date; however, in Uganda, only genotypes IX and X have been previously described. Inadequate ASF outbreak investigation has contributed to the delayed establishment of effective interventions to aid the control of ASF. Continuous virus characterization enhances the understanding of ASF epidemiology in terms of viral genome variations, extent, severity, and the potential source of the viruses responsible for outbreaks. We collected samples from pigs that had died of a hemorrhagic disea

SUBMITTER: Norbert Mwiine F 

PROVIDER: S-EPMC6463604 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature