Acute inflammation is associated with lower muscle strength, muscle mass and functional dependency in male hospitalised older patients.

ABSTRACT:

Background

Hospitalisation is associated with adverse health outcomes including loss of muscle strength, muscle mass and functional decline, which might be further aggravated by acute inflammation. This study aimed to determine whether acute inflammation, as denoted by C-reactive protein (CRP), is associated with muscle strength, muscle mass and functional dependency in hospitalised older patients.

Methods

The observational, prospective EMPOWER study included 378 hospitalised patients aged 70 years and older. As part of the hospital assessment, 191 patients (50.5%) had CRP measured. Muscle strength and mass were measured using handheld dynamometry and bioelectrical impedance analysis respectively. Activities of Daily Living (ADL) were assessed using Katz score and Instrument

SUBMITTER: Liu JYJ 

PROVIDER: S-EPMC6464173 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature