Feasibility and robustness of an oral HIV self-test in a rural community in South-Africa: An observational diagnostic study.

ABSTRACT:

Background

HIV-self-testing (HIVST) could be a strategy to get more people tested for HIV in resource limited settings. One of the prerequisites of a successful HIVST programme is the availability of an easy to use, valid HIV-test which is robust against field conditions and procedural errors by untrained lay users.

Methods and findings

The primary objective of this study was to evaluate the ability of untrained persons to correctly interpret the OraQuick HIV Self-Test results with oral fluid compared with results obtained by trained users using the matched lot OraQuick Rapid HIV-1/2 Antibody Test and blinded to the results of the Self-Test. Sensitivity of the OraQuick HIV Self-Test in untrained users was 101 in 102 (99.02%; 95%CI = 93.88-99.95%)-and specificity- 1,241 in 1,

SUBMITTER: Deville W 

PROVIDER: S-EPMC6464222 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature