Propofol versus thiopental sodium for the treatment of refractory status epilepticus.

ABSTRACT:

Background

This review is an update of a previously published review in the Cochrane Database of Systematic Reviews (Issue 6, 2015).Failure to respond to antiepileptic drugs in patients with uncontrolled seizure activity such as refractory status epilepticus (RSE) has led to the use of anaesthetic drugs. Coma is induced with anaesthetic drugs to achieve complete control of seizure activity. Thiopental sodium and propofol are popularly used for this purpose. Both agents have been found to be effective. However, there is a substantial lack of evidence as to which of the two drugs is better in terms of clinical outcomes.

Objectives

To compare the efficacy, adverse effects, and short- and long-term outcomes of refractory status epilepticus (RSE) treated with one of the two anaes

SUBMITTER: Prabhakar H 

PROVIDER: S-EPMC6464235 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature