High progesterone levels are associated with family history of premature coronary artery disease in young healthy adult men.

ABSTRACT:

Background & aims

The offspring of patients with premature coronary artery disease (P-CAD) are at higher risk for cardiovascular disease, compared with subjects without a family history (FH) of P-CAD. The increased risk for cardiovascular disease in subjects with FH of early-onset CAD results from unfavorable genetic variants as well as social, behavioral and environmental factors, which are more prevalent in this group. Previous studies have shown that specific sex hormone levels may be associated with the risk of cardiovascular disease. The aim of this study was to compare wide range of biochemical marker levels including i.e. the levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), progesterone, estradiol, testosterone and sex-hormone binding globulin (SHBG) b

SUBMITTER: Osadnik T 

PROVIDER: S-EPMC6464341 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature