FGMP: assessing fungal genome completeness.

ABSTRACT:

Background

Inexpensive high-throughput DNA sequencing has democratized access to genetic information for most organisms so that research utilizing a genome or transcriptome of an organism is not limited to model systems. However, the quality of the assemblies of sampled genomes can vary greatly which hampers utility for comparisons and meaningful interpretation. The uncertainty of the completeness of a given genome sequence can limit feasibility of asserting patterns of high rates of gene loss reported in many lineages.

Results

We propose a computational framework and sequence resource for assessing completeness of fungal genomes called FGMP (Fungal Genome Mapping Project). Our approach is based on evolutionary conserved sets of proteins and DNA elements and is applicable to

SUBMITTER: Cisse OH 

PROVIDER: S-EPMC6466665 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature