Combination of 15 lipid metabolites and motilin to diagnose spleen-deficiency FD.

ABSTRACT:

Background

This study aims to assess clinical characteristics in FD with spleen deficiency syndrome and metabolic perturbations involved in FD progress. We combined metabolic biomarkers and clinical features into a better prediction for FD with Spleen Deficiency syndrome.

Methods

A total of 276 people were recruited, including 215 FD patients and 61 healthy control group (HC). The clinical characteristics and gastric emptying rate were compared between spleen deficiency-FD group and non-spleen deficiency-FD. The serum lipids metabonomics analysis was performed to determine the metabolic differences in spleen deficiency-FD group and HC.

Results

The symptoms of postprandial discomfort in Spleen Deficiency group were more severe (P < 0.05), and delayed gastric emptying w

SUBMITTER: Zhang J 

PROVIDER: S-EPMC6466668 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature