Cu-Catalyzed Cross-Dehydrogenative ortho-Aminomethylation of Phenols.

ABSTRACT: A highly selective Cu^II -catalyzed cross-dehydrogenative ortho-aminomethylation of phenols with aniline derivatives is described. The corresponding C(sp² )-C(sp³ ) coupling products were obtained in moderate to excellent yields under mild reaction conditions and with a broad substrate scope. A radical mechanism is proposed.

SUBMITTER: Yu C 

PROVIDER: S-EPMC6468272 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature