Dataset Information
2,4 Dinitrophenol as Medicine.
Ontology highlight
ABSTRACT:
SUBMITTER: Geisler JG
PROVIDER: S-EPMC6468406 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
2,4 Dinitrophenol as Medicine.
Cells 20190323 3
In the sanctity of pure drug discovery, objective reasoning can become clouded when pursuing ideas that appear unorthodox, but are spot on physiologically. To put this into historical perspective, it was an unorthodox idea in the 1950's to suggest that warfarin, a rat poison, could be repositioned into a breakthrough drug in humans to protect against strokes as a blood thinner. Yet it was approved in 1954 as Coumadin<sup>®</sup> and has been prescribed to billions of patients as a standard of ca ...[more]