Tracing the phylogenetic history of the Crl regulon through the Bacteria and Archaea genomes.

ABSTRACT:

Background

Crl, identified for curli production, is a small transcription factor that stimulates the association of the σ^S factor (RpoS) with the RNA polymerase core through direct and specific interactions, increasing the transcription rate of genes during the transition from exponential to stationary phase at low temperatures, using indole as an effector molecule. The lack of a comprehensive collection of information on the Crl regulon makes it difficult to identify a dominant function of Crl and to generate any hypotheses concerning its taxonomical distribution in archaeal and bacterial organisms.

Results

In this work, based on a systematic literature review, we identified the first comprehensive dataset of 86 genes under the control of Crl in the bacterium Esc

SUBMITTER: Santos-Zavaleta A 

PROVIDER: S-EPMC6469107 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature